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OpenSim User Profile: Silvia Blemker, PhD

Simbios broadened University of Virginia’s Silvia Blemker’s horizons; and OpenSim is helping her understand hamstring injuries in sprinters.

from http://biomedicalcomputationreview.org/content/simbios-bringing-biomedical-simulation-your-fingertips   Silvia Blemker, PhD, has deep roots in Simbios. As a Stanford graduate student, she...
Oct, 01, 2009
Reaching Under the Hood of a 20-year-old Musculoskeletal Model

Confidence boost for modelers

It’s often said that all models are wrong, but some are useful. And one model that certainly falls in the “useful” category is the human lower-limb model that Scott Delp published...
Jun, 01, 2010
Simulating a Scaffold for Bone Growth

Using a 3-D computer model, scientists have simulated stem cells growing within a scaffold to predict which combination of  properties will produce the most bone

Designing a scaffold, the internal structure that helps patients regenerate bone, is a delicate balancing act. The scaffold must be strong enough to protect the injury, porous enough to allow...
Jan, 01, 2008
Representing Rotations with Quaternions
Many tasks in biomedical data analysis, such as kinematic data collection, involve 3-D motion analysis which requires precise representation of an object’s position and orientation. ...
Apr, 01, 2006
Particle Swarm Optimization: Taking a Cue from Mother Nature

Mimicking the social behavior of groups of animals to search for the minimum value of an objective function

Optimizing the solution to a problem occurs commonly in engineering and in nature.  The Particle Swarm Optimization (PSO) algorithm borrows ideas from nature and is a fairly new method of...
Jan, 01, 2007
Recognizing and Encouraging Timely Dissemination
The availability of free and open access data, models, and software indisputably accelerates scientific progress. Unfortunately, dissemination necessitates organization, documentation, and quality...
Jan, 01, 2010
Zooming In on Blood Coagulation and Viscosity: Computation Takes On Blood Behavior

Simulations illuminate the inner workings of blood at multiple levels

Understanding blood flow and coagulation is crucial to treating blood disorders such as hemophilia and thrombosis, and to dealing with diseases such as AIDS, malaria, and diabetes that have...
Jun, 07, 2012
The Ease and Grace of OpenSim 3.0

New release improves both GUI and API

OpenSim, the neuromuscular modeling and simulation software, is now available in a new digit: 3.0. The change (up from 2.4) reflects significant improvements that make this open source tool more...
OpenSim
Oct, 19, 2012
Meet the Skeptics: Why Some Doubt Biomedical Models - and What it Takes to Win Them Over

Disentangling the different types of skeptics and what modelers can learn from each.

What are the telltale signs of a modeling talk at a biology conference? Just look for the sighs, shifting, and eye-rolling in the audience, says Donald C. Bolser, PhD, professor of physiological...
Jun, 05, 2012
On Your Mark, Get Set, Build Infrastructure: The NCBC Launch

The first four National Centers for Biomedical Computing take off

WHY NATIONAL CENTERS? Four National Centers for Biomedical Computing were launched by the NIH in 2004 with $20 million in funding for each center over five years. The reason: We need to make...
Jun, 01, 2005
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