Computation offers a window into a disease often described as a black box
The growing threats of multi-drug resistant (MDR) and extensively drug resistant (XDR) tuberculosis (TB) are spurring worldwide interest in faster and more innovative research approaches, such as...
Jun, 06, 2012
POINT/
NO: Grant applications for the development and maintenance of software and infrastructure should compete with basic research applications.
Biomedicine has a strong...
Jul, 01, 2009
The National Institutes of Health Roadmap for Medical Research has recently completed the first stage of an ambitious program to expand the computational infrastructure and software tools needed to...
Jan, 01, 2006
A recognition of biocomputing's successes and a prediction of what's to come
The last ten years have seen huge leaps in biomedical computing. We now have new ways to integrate and understand vast quantities of data; the capacity for multi-scale biological modeling; and a...
bioinformatics tools, biomedical computing, CAD, computational modeling, data mining, disease surveillance, dynamic modeling, education, eric jakobsson, function prediction, genetic association, genome annotation, in silico screening, medical informatics, neuromodeling, prosthetics, sequence alignment, structure prediction, systems biology, systems biomedicine, telemedicine, tomography
Jun, 01, 2005
Biomechanical models contribute to a better understanding of both the normal and the diseased eye.
Squint, and you can almost make out that bird soaring over the horizon. But determining whether it’s a hawk or a raven will be nearly impossible for someone with myopia, also known as...
Feb, 19, 2013
Computation helps evaluate the nature of the NIH research portfolio in ways that were previously very difficult.
What biomedical research does the federal government fund? How is it allocated across important diseases? Has that changed over time? Answering these questions at any level of detail is tougher than...
Jun, 08, 2012
Predicting protein localization
Joe works in a factory; Jane works in a hospital; protein X works in the Golgi apparatus. Just as one might guess a worker’s job by knowing where he or she is employed, biologists can guess a...
Apr, 01, 2006
A virtual lab rat; simulated DNA; an artificial pancreas; & integrating mental health data
Several biomedical computing projects received multi-million dollar funding in the fall of 2011, including efforts to: simulate the cardiac physiology of the rat; build a state-of-the-art DNA...
Jan, 02, 2012
By computationally combining incomplete imaging information with bits and pieces of structural data from all sorts of different experiments, researchers have worked out the protein-by-protein structure of an important cellular assembly called the nuclear pore complex.
Like puzzles? Here’s a tough one: Try figuring out the construction of a nearly 500-piece machine without blueprints or a complete picture. Biologists have now accomplished just such a feat,...
Apr, 01, 2008
The study of HIV evolution is not only critical to fighting the virus; it has also driven advances in the computational tools used to study evolution in general.
When Darwin published On the Origin of Species in 1859, it would be decades before HIV would jump from monkeys to humans and set off a devastating worldwide pandemic. But evolution is at the heart of...
Jul, 01, 2009