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Behind the Connectome Commotion

Exploring the current state of connectomics--in the midst of hype

Connectomics is having a moment. Following on the heels of genomics, proteomics, transcriptomics, metabolomics, and microbiomics, the latest “omic” to seize the spotlight is generating...
brain, connectome
Jun, 20, 2013
Sparks of Hope for a More Open Approach to Scientific Research and Publishing

Transparent peer review, replication studies, and journals of negative results all suggest change is on the horizon

As I was writing this editorial, I learned about yet another scientific paper being retracted. This time it was a genetics paper in Science, one of the hundreds of retractions that the blog...
errors, peer review, replication, scientific publication
Sep, 01, 2011
Profiles in Computer Science Courage Part II: Advice on Taking the Plunge
Words of Advice from the Scientists Featured in Profiles in Computer Science Courage   Find  Your Passion “Not every computer scientist will fall in love with the field like I did,...
Apr, 01, 2011
Profiles in Computer Science Courage Part I: Reflections on the rewards of plunging into biomedicine

Interviews with Leonidas Guibas, Ron Shamir, Michael Black, David Haussler, Daphne Koller, Erin Halperin, Gene Myers, Paul Groth and Bruce Donald

To a computer scientist, the fields of biology and medicine can seem like the vast Pacific Ocean, says Leonidas Guibas, PhD, professor of computer science at Stanford University. “You go to the...
Careers, computer science
Apr, 01, 2011
2012 Update on the National Centers for Biomedical Computing

The Principal Investigators weigh in

Ever since the National Institutes of Health (NIH) began funding the National Centers for Biomedical Computing (NCBCs) just over seven years ago, these powerhouses have been plugging away, building...
NCBC
Feb, 29, 2012
The Function of DNA Form
According to a new computational analysis of DNA structure, variations in DNA shape—along the grooves of the double helix—may play an important role in defining how the genome works. The...
Jul, 01, 2009
On Your Mark, Get Set, Build Infrastructure: The NCBC Launch

The first four National Centers for Biomedical Computing take off

WHY NATIONAL CENTERS? Four National Centers for Biomedical Computing were launched by the NIH in 2004 with $20 million in funding for each center over five years. The reason: We need to make...
Jun, 01, 2005
Editor's Picks
One of our goals at Biomedical Computation Review is to create a sense of kinship among members of this very diverse community of researchers. This column provides reviews of some of the latest and...
Jun, 01, 2005
Modeling Sperm: The Finer Points of Fertilization

Navigating the oviduct and other mysteries

The essential elements of human fertilization are clear: sperm swim through the uterus, travel up the fallopian tube, and fertilize an egg. Not as well understood are the the nitty-gritty details of...
agent-based models, fertilization, sperm
Jun, 19, 2013
Simbios: Bringing Biomedical Simulation to Your Fingertips

How Simbios' state-of-the-art software tools are contributing to high-impact biomedical research

Simbios began with a simple idea: that physics-based simulation of biological structures at all scales could benefit from a unified tool-building effort.   At the same time, the thinking went,...
Oct, 01, 2009
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