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Follow the Money: Big Grants in Biomedical Computing

A virtual lab rat; simulated DNA; an artificial pancreas; & integrating mental health data

Several biomedical computing projects received multi-million dollar funding in the fall of 2011, including efforts to: simulate the cardiac physiology of the rat; build a state-of-the-art DNA...
diabetes, DNA, Orozco, pancreas
Jan, 02, 2012
VIEW THIS ISSUE IN PDF
Feb, 22, 2012
Point/Counterpoint: Clinical Data Repositories: Less than meets the eye OR More valuable than you'd expect?
POINT/ Less than meets the eye                                             ...
Oct, 05, 2012
The Epigenome: A New View Into the Book of Life

There is growing recognition that epigenetics may be just as important as genetics in human health and disease.

In the early 19th century, Jean-Baptiste Lamarck explained evolution as the inheritance of acquired traits; he believed that changes due to behaviors and exposures in one generation could be passed...
Jun, 01, 2010
New Algorithm Finds Stories in Biomedical Literature

Algorithm joins related publications in a chain from start to finish

A good story ties up all the loose ends. A new data-mining tool takes a stab at doing the same. Dubbed storytelling, the algorithm may make it easier to unearth unexpected connections in the...
Jan, 01, 2007
Genetic Variants and Ill Health: Scanning 500,000 SNPs Yields Gene-Disease Connections

It's an exhilarating time for genome-wide association studies

For the past few months it seemed you couldn’t open a journal without reading results of a new genome-wide association study. The results kept pouring in: four studies in April showing seven...
Oct, 01, 2007
Getting It Right: Better Validation Key to Progress in Biomedical Computing

Bringing models closer to reality

When the ill-fated space shuttle Columbia launched on January 16, 2003, a large piece of foam fell off and hit the left wing. Alerted of the impact, NASA engineers used a computer model to predict...
7009, competitions, outsource, self-assessment, validation
Oct, 19, 2012
Microarrays: The Search For Meaning in a Vast Sea of Data

They've gone from hype to backlash. Now it's time for reality: How microarrays are being used to benefit healthcare

When DNA microarray technology emerged more than a decade ago, it was met with unbridled enthusiasm. By allowing scientists to look at the expression of enormous numbers of genes in the genome...
Oct, 01, 2006
Editor's Picks
One of our goals at Biomedical Computation Review is to create a sense of kinship among members of this very diverse community of researchers. This column provides reviews of some of the latest and...
Jun, 01, 2005
Mining Biomedical Literature: Using Computers to Extract Knowledge Nuggets

Researchers are not simply retrieving and repackaging what is already known, but are also deriving new knowledge by discovering connections that were previously unnoticed.

Not long ago, reading biomedical literature involved hours in the library combing through rows of dusty periodicals—not to mention pocketfuls of change for the copy machine. Now, although the...
Jul, 01, 2008
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