A closer look at the curation of models discussed in The Physiome: A Mission Imperative
Multi-scale quantitative models need to be validated and reproducible if they are to be useful for clinical workflows, says Hunter. The Physiome infrastructure developed by Hunter, Dr Poul Nielsen...
Jun, 01, 2010
How researchers are combining disparate data types and simulating systems that contain many different moving parts
13 years ago Markus Covert, PhD, read a New York Times article that changed his life. The article quoted a prominent microbiologist who suggested that the ultimate test of one’s...
Feb, 16, 2013
How adding jet packs to characters' hands can help optimize animations
An animated human figure seeking the optimal path from point A to point B typically relies on computationally expensive hard constraints that force the trajectories to be physically realistic. But...
Jun, 20, 2013
Medicinal patches applied to the skin are an attractive route for drug delivery since they can release medicine slowly into the bloodstream and avoid being metabolized by the digestive system. Yet...
Oct, 01, 2009
Using packing software to convey humanity’s complex relationship with HIV in short films or images
Three-D animators have long sought algorithms that can pack odd-shaped things into tight spaces. Now, Graham Johnson, PhD, a QB3 Faculty Fellow in bioengineering at the University of California, San...
Feb, 19, 2013
Through RNABuilder, Simbios brings computational modeling to Rick Russell’s lab at the University of Texas.
from http://biomedicalcomputationreview.org/content/simbios-bringing-biomedical-simulation-your-fingertips
Rick Russell, PhD, associate professor of chemistry and biochemistry at the...
Oct, 01, 2009
How increased coverage of the structure space is transforming the field of biology
When the human genome was completely sequenced in 2003, researchers were already pondering how biomedicine could make use of it. One hope was that the sequences would lead to a greater...
Jan, 01, 2010
The new Big Data to Knowledge (BD2K) program signals NIH's faith in computational research
In December, the National Institutes of Health (NIH) approved a new trans-NIH initiative called Big Data to Knowledge (BD2K). With this action, the NIH signals its intention to invest a significant...
Feb, 19, 2013
Biomarker research, genetics, and imaging are all coming into play
In 1906, at a small medical meeting in Tübingen, Germany, physician Alois Alzheimer gave a now-famous presentation about a puzzling patient. At age 51, Auguste D.’s memory was failing...
Oct, 01, 2007
A combination of genomics data and molecular dynamics modeling is sufficient to predict protein complex structure
The zone where two proteins interact presents a possible target for drug design. But identifying possible drugs requires a detailed understanding of the interface between the proteins. Computer...
Apr, 01, 2010