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An insider’s view of biological structures
In March, Simbios released version 1.0 of the SimTK Simulation toolkit. A cornerstone of this release is Simbody, a new piece of the open-source SimTK Core toolkit for physics-based simulation....
Apr, 01, 2008
A Giant Leap for Open Source Simulation
Researchers can now create musculoskeletal models and simulations on an open source platform. In August, Simbios researchers released OpenSim 1.0. This freely available software can, in about 20...
Oct, 01, 2007
Cell Division’s Surprise Twist
During the final step of cell division, a ring of proteins pinches the cell in two—a process often likened to a purse string drawing shut. The analogy evokes a picture of thread-like proteins...
Apr, 01, 2008
Three New Centers
The National Institutes of Health Roadmap for Medical Research has recently completed the first stage of an ambitious program to expand the computational infrastructure and software tools needed to...
Jan, 01, 2006
The Ease and Grace of OpenSim 3.0

New release improves both GUI and API

OpenSim, the neuromuscular modeling and simulation software, is now available in a new digit: 3.0. The change (up from 2.4) reflects significant improvements that make this open source tool more...
OpenSim
Oct, 19, 2012
OpenSim User Profile: Silvia Blemker, PhD

Simbios broadened University of Virginia’s Silvia Blemker’s horizons; and OpenSim is helping her understand hamstring injuries in sprinters.

from http://biomedicalcomputationreview.org/content/simbios-bringing-biomedical-simulation-your-fingertips   Silvia Blemker, PhD, has deep roots in Simbios. As a Stanford graduate student, she...
Oct, 01, 2009
Dock This: In Silico Drug Design Feeds Drug Development

As algorithms evolve, computing power explodes, and scientists solve a greater number of 3-D protein structures, computer-aided design has the potential to dramatically cut the cost and time of drug discovery

Once upon a time, not long ago, HIV/AIDS was a scourge, killing anyone who contracted the deadly virus. Now, many people are living with the disease, which they control with drugs initially developed...
Jul, 01, 2007
Computing the Ravages of Time: Using Algorithms To Tackle Alzheimer’s Disease

Biomarker research, genetics, and imaging are all coming into play

In 1906, at a small medical meeting in Tübingen, Germany, physician Alois Alzheimer gave a now-famous presentation about a puzzling patient. At age 51, Auguste D.’s memory was failing...
Oct, 01, 2007
Grand Challenge Competition Provides Rich Data Set to Improve Joint Contact Force Predictions
There are numerous musculoskeletal modeling methods available to make predictions of muscle and joint contact forces. While such predictions can help improve treatments for movement-related disorders...
knee
Jan, 02, 2012
Computational Biomechanics: Making Strides Toward Patient Care

Moving from intuition to evidence-based intervention

To understand how muscles contract and joints flex, researchers have dissected cadavers and experimented with animals. They can describe how bones, muscles, and tendons connect in a complicated...
Jan, 01, 2007
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