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Making DNA Smile

Researcher coaxes long strands of DNA into predetermined geometric shapes

Designing nanostructures of DNA just got easier. Paul Rothemund, PhD, a senior research fellow at Caltech has found a way to coax a long strand of DNA into a predetermined geometric shape by mixing...
Jul, 01, 2006
Allen Brain Atlas Launched
In three dimensions, researchers can now visualize the location and activity of more than 21,000 genes in a normal mouse brain.  The Allen Brain Atlas, funded with $100 million in seed money...
Jan, 01, 2007
Infrastructure and Workforce Needs in Biomedical Informatics and Computational Biology
In science, there is a need to balance research in domain sciences and the infrastructure to support that research. Basic research mediated through peer review is understood to produce useful...
Jan, 01, 2007
Simulated Lipid Rafts
According to traditional theory, lipid membranes consist of a “fluid-mosaic” in which molecular components, including membrane proteins, are randomly distributed and move freely against a...
Apr, 01, 2007
Remodeling by Curvature

Simulating how cell membranes form vesicles

Whenever a cell needs to get rid of waste, transport materials, sort proteins, or build new organelles, membranes remodel themselves. Often that means forming small enclosed compartments called...
Jul, 01, 2007
From Sight to Insight: Visualization tools yield biomedical success stories
They're more than just pretty pictures adorning office walls and presentation slides. Beamed into operating room computer monitors, they're guiding the scalpels of brain surgeons. Dancing...
Jan, 01, 2012
Dealing With a Flood of Conformations Using MSMBuilder
In the world of molecular dynamics (MD), researchers often need to analyze and extract meaningful results from millions of conformations. Existing software for accomplishing this task focuses on...
Oct, 01, 2009
Sensational Sequences

A new media artwork explores novel ways to represent and intuitively understand nature in the metagenomic era

What’s it like to be immersed in a dataset of millions of DNA sequences? Audiences of ATLAS in silico—a new media artwork that explores novel ways to represent and intuitively understand...
Oct, 01, 2008
Simulation Simplified

Simbody introduces the concept of a “mobilizer,” which directly expresses a part’s movement, however complex, purely in relation to another part

Typically, researchers who simulate life in motion—from particles to people—start by describing the motion of each part of an object independently of the other parts. Additional equations...
Jan, 01, 2008
Swine Dynamics
The antiviral drugs Tamiflu and Relenza target a key flu protein—neuraminidase—preventing it from doing its job of releasing virus particles from infected cells into the body. The type of...
Jul, 01, 2009
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