Scientists have long wondered how many genes are necessary to support life. This knowledge could be used to construct new forms of artificial life to efficiently produce better biofuels or drugs....
Jan, 01, 2008
Current methods of tracking the flu all come with a bit of a time lag—which is unfortunate when trying to monitor for potential pandemics like today’s swine flu crisis. There is a faster...
Jul, 01, 2009
Many a successful investigator working at the interface between molecular biology, genetics and computation will recognize the imperative to obtain biological validation for computational...
Jul, 01, 2008
A new media artwork explores novel ways to represent and intuitively understand nature in the metagenomic era
What’s it like to be immersed in a dataset of millions of DNA sequences? Audiences of ATLAS in silico—a new media artwork that explores novel ways to represent and intuitively understand...
Oct, 01, 2008
Set objectives and follow through
Having engineered several scientific software applications for public consumption, the authors know from experience that the process offers unique challenges. Typically, the algorithms being...
Oct, 22, 2012
Researchers examine the connection between editorial boards of medical informatics and bioinformatics journals
How ideas spread gets at the very fabric of scholarly research and has been studied from many different angles.
Many studies examine person-to-person connectivity in social networks. Within a...
Jul, 01, 2007
Pursuing the frontiers of systems biology in an interdisciplinary, non-academic enviroment
The Institute for Systems Biology (ISB) was founded in Seattle, Washington in 2000 by Leroy Hood, MD, PhD, Alan Aderem, PhD, and Reudi Aebersold, PhD. Five years later, they are pursuing the...
Apr, 01, 2006
Computation offers a window into a disease often described as a black box
The growing threats of multi-drug resistant (MDR) and extensively drug resistant (XDR) tuberculosis (TB) are spurring worldwide interest in faster and more innovative research approaches, such as...
Jun, 06, 2012
New approaches extend multiscale models to represent cellular mesoscales and bridge from molecular to cellular models
In an era of increasingly comprehensive molecular characterizations of living systems, computation has emerged as a key technology to facilitate integrative understanding of biological mechanisms....
Feb, 19, 2013
Neighbor cells affect stem cell differentiation in computer simulation
Every generation, a few nonconformists crop up in tissue cultures of genetically identical cells. The question is: are the wayward simply born that way, or did something in the environment affect...
Jul, 01, 2007