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Misconceptions of Time

Getting the molecular dynamics car out of the garage

For those who are not practitioners of dynamical simulation methods, such as molecular dynamics (MD), one of the biggest misconceptions relates to time. Specifically, the mismatch between the...
molecular dynamics simulations, time
Jun, 19, 2013
BCATS: Not Your Usual Biomedical Computation Conference

Students, not faculty, are the ones in charge

Outwardly, the Biomedical Computation at Stanford (BCATS) conference resembles other academic conferences: Researchers converge to hear about the latest developments in their field and to...
Jan, 01, 2008
Predicting the Structure of Important Drug Receptors

Structure-prediction algorithm searches for most likely conformation

If you want to find a Tab ‘A’ that will fit into a Slot ‘B’, you’ll waste a lot of time if you don’t know the shape of the slot. For scientists trying to design...
Jul, 01, 2006
On Simulating Growth and Form

Simulations can teach us how young bodies and faces develop; how an artery compensates for decades of fatty plaque deposits by growing and thickening its walls; how tissue engineers can best coax endothelial cells to develop into organized sheets of skin for burn patients; and how cancerous tumors invade neighboring tissue.

For better or for worse, and on many levels, our tissues never stop growing and changing. While developing from childhood to old age, we grow not only bone, cartilage, fat, muscle and skin, but also...
Apr, 01, 2008
A Model of Epstein— Barr Virus

A new simulation mimics the virus’s infection cycle on the tonsils, shedding some light on how the infection spreads

During our lives, most of us will come in contact with the Epstein-Barr virus, commonly known as that bane of teenagers, infectious mononucleosis. Now, a new simulation mimics the virus’s...
Jan, 01, 2008
Zooming In on Blood Coagulation and Viscosity: Computation Takes On Blood Behavior

Simulations illuminate the inner workings of blood at multiple levels

Understanding blood flow and coagulation is crucial to treating blood disorders such as hemophilia and thrombosis, and to dealing with diseases such as AIDS, malaria, and diabetes that have...
Jun, 07, 2012
Modeling Cancer Biology: Reaching beyond human intuition and linear thinking

How mathematical models are transforming the fight against cancer

The most common test for prostate cancer (known as PSA screening) misses aggressively growing prostate tumors—the type typically seen in young patients. It’s a fact that was accepted by...
Apr, 01, 2007
Integrative Cancer Biology Program is Born
The National Cancer Institute launched the Integrative Cancer Biology Program (ICBP) in October 2004, providing a total of $15 million to nine multidisciplinary centers. The goal: to use predictive...
cancer, integrative
Jun, 01, 2005
SimVascular User Profile: Charles Taylor, PhD

Charles A. Taylor, PhD, associate professor of bioengineering at Stanford University, is PI for the cardiovascular dynamics project within Simbios.

from http://biomedicalcomputationreview.org/content/simbios-bringing-biomedical-simulation-your-fingertips   Cardiovascular disease is a primary source of morbidity and mortality in the United...
Oct, 01, 2009
Simulated Metabolism -- A First Step Toward Simulated Cells

Having developed detailed and sophisticated models of both E. Coli and human metabolism, researchers can begin to build toward a whole cell model that will be useful for the study of human health and disease.

If biologists really understood the functioning of the genome, they could in principle recreate it in silico. Instead of a choreographed swirl of molecules inside a living cell, electrons...
Oct, 01, 2008
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