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Bridging the Scientific Divide: Enabling Sharing through Biomedical Computing

How to share knowledge, data, tools, and computational resources in a sustainable manner

Once upon a time, a deep divide existed between scientists who did and those who did not have easy access to scientific content (journals, lectures, data), hardware (imaging devices, lab instruments...
sharing
Apr, 01, 2011
Profiles in Computer Science Courage Part I: Reflections on the rewards of plunging into biomedicine

Interviews with Leonidas Guibas, Ron Shamir, Michael Black, David Haussler, Daphne Koller, Erin Halperin, Gene Myers, Paul Groth and Bruce Donald

To a computer scientist, the fields of biology and medicine can seem like the vast Pacific Ocean, says Leonidas Guibas, PhD, professor of computer science at Stanford University. “You go to the...
Careers, computer science
Apr, 01, 2011
Semantic Publishing and Scientific Journals
Keeping up with the literature is a challenge for all scientists. But some researchers are making it easier by enhancing the usability and understanding of an article’s contents in a variety of...
Jul, 01, 2009
Microarrays: The Search For Meaning in a Vast Sea of Data

They've gone from hype to backlash. Now it's time for reality: How microarrays are being used to benefit healthcare

When DNA microarray technology emerged more than a decade ago, it was met with unbridled enthusiasm. By allowing scientists to look at the expression of enormous numbers of genes in the genome...
Oct, 01, 2006
Janelia Farm: Cultivating Scientists

Janelia farmers pursue novel, cross-disciplinary collaborations to work on long-term, unwieldy scientific problems difficult to tackle in a single laboratory

The folks at Howard Hughes Medical Institute who dreamed up Janelia Farm say it is as much a social innovation as a scientific one. “We are creating a different culture here,” says Gerald...
Jul, 01, 2006
Point/Counterpoint: Should there be a separate funding mechanism for the development and maintenance of software and infrastructure?
  POINT/   NO:  Grant applications for the development and maintenance of software and infrastructure should compete with basic research applications. Biomedicine has a strong...
Jul, 01, 2009
The Female Factor: Is the gender gap in computer science carrying over to biomedical computing?

Early evidence suggests a mixed picture

Stanford University’s 2004-2005 computer science T-shirts exhibited symbols for six men and one woman -- an accurate portrayal of the ratio in the department and only slightly worse than the...
Apr, 01, 2006
The Epigenome: A New View Into the Book of Life

There is growing recognition that epigenetics may be just as important as genetics in human health and disease.

In the early 19th century, Jean-Baptiste Lamarck explained evolution as the inheritance of acquired traits; he believed that changes due to behaviors and exposures in one generation could be passed...
Jun, 01, 2010
The Ease and Grace of OpenSim 3.0

New release improves both GUI and API

OpenSim, the neuromuscular modeling and simulation software, is now available in a new digit: 3.0. The change (up from 2.4) reflects significant improvements that make this open source tool more...
OpenSim
Oct, 19, 2012
Computing the Ravages of Time: Using Algorithms To Tackle Alzheimer’s Disease

Biomarker research, genetics, and imaging are all coming into play

In 1906, at a small medical meeting in Tübingen, Germany, physician Alois Alzheimer gave a now-famous presentation about a puzzling patient. At age 51, Auguste D.’s memory was failing...
Oct, 01, 2007
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