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Computational Biomechanics: Making Strides Toward Patient Care

Moving from intuition to evidence-based intervention

To understand how muscles contract and joints flex, researchers have dissected cadavers and experimented with animals. They can describe how bones, muscles, and tendons connect in a complicated...
Jan, 01, 2007
Different But Equal
Kids often claim they are just as smart—if not smarter—than their parents. Childish nonsense? Perhaps not, according to a recent study. It turns out that young children’s brains are...
Oct, 01, 2009
Scale-Free Networks in Contemporary Biology
A standard dictionary definition of a network is “an interconnected or interrelated chain, group, or system.” A cursory look at our surroundings shows that networks are ubiquitous. For...
Oct, 01, 2007
Neurocomputation of Music, Faces and Belly Laughs

Pattern-classifiers interpret fMRI data

Peek inside the skull of a couch potato watching reruns on TV and you’ll see non-stop patterns of blood flow throughout the brain. If you learn to pick out which activity patterns match up with...
Oct, 01, 2010
Turning Therapeutic Antibodies into Better Drugs

A computer algorithm manipulates antibodies to predict which forms will bind their targets more tightly

The word “antibody” conjures images of our bodies fighting off bacteria and viruses. But because they can latch onto their targets with great precision, antibodies are also used to treat...
Jan, 01, 2008
FOLLOW THE MONEY: Big Grants in Biomedical Computing

Several big-dollar initiatives received NIH funding in late 2010

In the current economic climate, every research dollar counts. Fortunately, when it comes to biomedical computing, not everyone has been left counting change. Several big-dollar initiatives received...
brain, immunity, network
Apr, 01, 2011
Jackson Pollock’s Protein Interaction Communities

Plot shows how functional communities in yeast protein interaction networks change in size and nature at different levels of resolution

Splashes of bold color seem to drip down the page, bringing to mind the paintings of Jackson Pollock. Spurred by the beauty of the image she had created, Anna Lewis,* a graduate student studying...
protein interaction networks
Apr, 01, 2011
Predicting Brain Response To Nouns

Capturing meaning in functional MRI

Thinking of a noun—a peach, train, or bird, for example—activates specific parts of the brain.  Now, scientists have trained a computer to predict such activation patterns. The...
Oct, 01, 2008
NewsBytes: Winter 2005-2006
T-Rex in the Slow Lane by Kristen Cobb   Tyrannosaurus rex is often pictured baring its teeth, crouching, and running swiftly after its prey, but these images are largely based on human fancy...
Jan, 01, 2006
Window into Microbial Behavior

Metagenomes give a picture of the genes driving metabolic processes important to bacterial growth and survival in different environments.

We know they are there, but most microbial denizens of deep oceans, sea floor vents, even our own intestines, remain a mystery. Because most microbes won’t grow in the lab, researchers have few...
Jul, 01, 2008
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