Even when we simply stand still on two feet, our brains communicate with our muscles—firing them appropriately to keep us upright against gravity. So when scientists simulate simple or complex...
Jun, 06, 2012
Simulating molecular movement gives a more accurate view of binding sites.
If a picture’s worth a thousand words, then a motion picture, such as that provided by molecular dynamics (MD) simulations, must contain a wealth of information. It’s this potential...
Oct, 01, 2008
Moving from intuition to evidence-based intervention
To understand how muscles contract and joints flex, researchers have dissected cadavers and experimented with animals. They can describe how bones, muscles, and tendons connect in a complicated...
Jan, 01, 2007
In March, Simbios released version 1.0 of the SimTK Simulation toolkit. A cornerstone of this release is Simbody, a new piece of the open-source SimTK Core toolkit for physics-based simulation....
Apr, 01, 2008
Simulations can teach us how young bodies and faces develop; how an artery compensates for decades of fatty plaque deposits by growing and thickening its walls; how tissue engineers can best coax endothelial cells to develop into organized sheets of skin for burn patients; and how cancerous tumors invade neighboring tissue.
For better or for worse, and on many levels, our tissues never stop growing and changing. While developing from childhood to old age, we grow not only bone, cartilage, fat, muscle and skin, but also...
Apr, 01, 2008
How precise an image can fluorescence microscopy provide?
As modern optics and cell biology have flourished in recent years, they’ve each driven innovation in the other. Yet commonly employed imaging techniques, such as fluorescence microscopy, have...
Sep, 01, 2011
Atomistic simulations have the potential to elucidate the molecular basis of biological processes such as protein misfolding in Alzheimer’s disease or the conformational changes that drive...
Jan, 01, 2010
Li Niu of the University of Albany works with Simbios to understand an unusual RNA.
from http://biomedicalcomputationreview.org/content/simbios-bringing-biomedical-simulation-your-fingertips
Li Niu, PhD, associate professor of chemistry at the University of Albany, SUNY found...
Oct, 01, 2009
How errors in data, software, and methodology can teach us how to do better
In 2006, a paper in Nature Medicine suggested a novel and potentially revolutionary method for predicting patient responses to cancer therapies using gene signatures. The finding piqued the interest...
Sep, 01, 2011
Notre Dame’s Jesus Izaguirre collaborates with Simbios to increase the time scales of protein folding simulations with OpenMM. Why team up with Simbios? Because “they are working on exciting problems and have good people,” he says.
from http://biomedicalcomputationreview.org/content/simbios-bringing-biomedical-simulation-your-fingertips
Jesus Izaguirre, PhD, associate professor of computer science and engineering at the...
Oct, 01, 2009