Advances in computational power and algorithms have led to longer and more accurate molecular dynamics simulations of protein folding. But these approaches, because they are computationally intensive...
Jun, 06, 2012
There is growing recognition that epigenetics may be just as important as genetics in human health and disease.
In the early 19th century, Jean-Baptiste Lamarck explained evolution as the inheritance of acquired traits; he believed that changes due to behaviors and exposures in one generation could be passed...
Jun, 01, 2010
Supercomputers open up new horizons, offering the possibility of discovering new ways to understand life’s complexity
Their very names sound like dinosaurs. Teracomputers. Petacomputers. These are, in fact, the dinosaurs of the digital world—monstrous, hungry and powerful. But unlike the extinct...
Oct, 01, 2006
Researcher coaxes long strands of DNA into predetermined geometric shapes
Designing nanostructures of DNA just got easier. Paul Rothemund, PhD, a senior research fellow at Caltech has found a way to coax a long strand of DNA into a predetermined geometric shape by mixing...
Jul, 01, 2006
Katherine Holzbaur of Wake Forest University Medical School simulates the biomechanics of the upper limb.
from http://biomedicalcomputationreview.org/content/simbios-bringing-biomedical-simulation-your-fingertips
Katherine Holzbaur, PhD, assistant professor of biomedical engineering at Wake Forest...
Oct, 01, 2009
Simbios broadened University of Virginia’s Silvia Blemker’s horizons; and OpenSim is helping her understand hamstring injuries in sprinters.
from http://biomedicalcomputationreview.org/content/simbios-bringing-biomedical-simulation-your-fingertips
Silvia Blemker, PhD, has deep roots in Simbios. As a Stanford graduate student, she...
Oct, 01, 2009
The National Institutes of Health Roadmap for Medical Research has recently completed the first stage of an ambitious program to expand the computational infrastructure and software tools needed to...
Jan, 01, 2006
Before categorizing things, you have to decide on the categories. For material “things” (e.g., molecules, organs, etc.) or entities, the task is relatively straightforward. But...
Oct, 01, 2010
Gene therapy to correct inherited illnesses hinges on successful delivery of DNA into a person’s cells. Most gene therapists work with viruses to ferry their DNA cargo. Yet the body tends to...
Oct, 01, 2009
The Fall 2005 “Under the Hood” column discussed the curse of dimensionality—too many numerical components for each data point—and the curse of dataset sparsity—too few...
Oct, 01, 2010